Results


AMN060

2014 - 2017

Control of Campylobacter jejuni in chickens by vaccination

Principal Investigator: Shayan Sharif, University of Guelph
Co-investigator: Mario Monteiro, Jennifer Brisbin, Carlton Gyles, Tamiru Negash Alkie, Douglas Hodgins, University of Guelph
Status: In progress

Background

Research by others has shown a vaccine can control Campylobacter jejuni in mouse and primate models. A pilot study conducted at the University of Guelph has since shown the vaccine reduces numbers of C. jejuni in the chicken gut of up to 100-fold. It is estimated that a 1000-fold decrease combined with other measures, such as biosecurity, could decrease the number of cases of human campylobacteriosis by 90%. With the objective of this level of control, the researchers are taking much of what they know about chicken immune responses to avian influenza vaccine to develop a strategy to improve the performance of the campylobacter vaccine.

Funding

$170,000 ($60,000 CPRC, $25,000 PIC, $85,000 NSERC)

Status report coming soon


Back to results