January 2016 - December 2018

Microbiome manipulations of the chicken GI tract as a route to maintain poultry health

Principal Investigator: John Parkinson, Hospital for Sick Children/University of Toronto
Co-investigator: John Brumell, The Hospital for Sick Children/University of Toronto; David Guttman, University of Toronto; Doug Korver, University of Alberta; Shayan Sharif, University of Guelph
Status: In progress


With increasing public pressure to eliminate growth promoting antibiotics (GPAs) from the Canadian poultry industry, affordable and broadly implementable alternatives that minimize risk of infection from enteric pathogens such as Clostridium perfringens, are urgently needed. While recent studies have demonstrated the potential of probiotics to reduce pathogen burden in the GI tract, it is not clear how they work or which formulations are most efficacious. The project will  investigate the molecular basis by which probiotic formulations protect against infection and compare the performance of currently employed probiotics against a panel of formulations.


$621,700 (CPRC $40,000, ALMA $240,000, NSERC Discovery $50,000, Lallemand Animal Nutrition $45,000, Pitblado Chair $30,000, Hospital for Sick Children $92,400 (in-kind), University of Toronto $23,100 (in-kind),  University of Alberta $46,200 (in-kind), New Life Mills $45,000 (in-kind), Aviagen $10,000 (in-kind))

Status report coming soon

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